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US 2014/0363858 A1Published application
Methods for hydroxylating phenylpropanoids
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsYAJUN YAN, YUHENG LIN
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Abstract
Provided herein are methods for producing an ortho-hydroxylated phenylpropanoid. In one embodiment the method includes culturing a microbe that includes HpaBC activity in the presence of a phenylpropanoid substrate. Also provided are genetically engineered microbes engineered to have greater levels of HpaB and/or HpaC than a control microbe.
Claims24
A method for producing an ortho-hydroxylated phenylpropanoid comprising:
- culturing a microbe comprising an HpaBC activity in the presence of a phenylpropanoid substrate under conditions suitable to ortho-hydroxylate the phenylpropanoid substrate to result in an ortho-hydroxylated phenylpropanoid;
- and
- isolating the ortho-hydroxylated phenylpropanoid from the microbe or the culture medium, or the combination thereof.
A genetically engineered microbe comprising greater HpaBC activity than a control microbe.
Dependencies are inferred from the claim text.