Genetic test for liver copper accumulation in dogs

The method according to any one of the preceding claims, further comprising detecting in a sample the presence or absence in the genome of the dog of one or more SNPs selected from BICF2P506595 (SEQ ID NO:

• 1), BICF2P772765 (SEQ ID NO:2), BICF2S2333187 (SEQ ID NO:3), BICF2P1324008 (SEQ ID NO:4), BICF2P591872 (SEQ ID NO:5), ATP7a_Reg4_F—9 (SEQ ID NO:
• 131), UBL5_Reg1F—16 (SEQ ID NO:
• 132), golga5_Reg1—24 (SEQ ID NO:
• 133), golga5—26 (SEQ ID NO:
• 134), golga5—27 (SEQ ID NO:
• 135), golga5—28 (SEQ ID NO:
• 136), golga5—29 (SEQ ID NO:
• 137), golga5—30 (SEQ ID NO:
• 138), golga5—31 (SEQ ID NO:
• 139), atp7areg17—32 (SEQ ID NO:
• 140), atp7areg17—33 (SEQ ID NO:
• 141) and one or more SNPs in linkage disequilibrium thereof.

The method according to any one of the preceding claims, comprising detecting in a sample the presence or absence in the genome of the dog of:

• (a) Chr22—3167534 (SEQ ID NO:
• 144), Chr22—3135144 (SEQ ID NO:
• 145), Chr20—55461150 (SEQ ID NO:
• 146), Chr19—6078084 (SEQ ID NO:
• 148), Chr3—86838677 (SEQ ID NO:
• 152), Chr10—65209946 (SEQ ID NO:
• 155) and ChrX—63338063 (SEQ ID NO:
• 142);
• or
• (b) ChrX—120879711 (SEQ ID NO:
• 147), Chr15—62625262 (SEQ ID NO:
• 149), Chr22—3167534 (SEQ ID NO:
• 144), Chr8—4892743 (SEQ ID NO:
• 157), Chr24—4011833 (SEQ ID NO:
• 153) and Chr18—60812198 (SEQ ID NO:
• 154).