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US 2014/0350401 A1Published application
Carotid body ablation via directed energy
OwnerYegor D. SINELNIKOVinventor
Life of this patent
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Abstract
Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
Claims25
A system for endovascular ultrasound ablation comprising:
- an ultrasound imaging device;
- an endovascular ultrasound treatment catheter;
- and
- a control unit,
- wherein the endovascular ultrasound treatment catheter is configured to emit an ultrasound pulse having a pulse repetition frequency that is a harmonic of a pulse repetition frequency of an ultrasound pulse emitted from the external ultrasound imaging probe such that the region of tissue receiving the ultrasound pulse emitted by the treatment catheter is distinguished from the surrounding tissue on a sonogram.
2 more elements
A method of imaging a region of tissue receiving ultrasound ablation targeting energy, comprising:
- delivering an imaging ultrasound pulse from an imaging ultrasound transducer towards target tissue;
- delivering an ablation targeting ultrasound pulse from an endovascularly positioned ablation ultrasound transducer towards the target tissue, the ablation targeting pulse having a pulse repetition frequency that is a harmonic or sub-harmonic of a pulse repetition frequency of the imaging ultrasound pulse;
- and
- super-positioning echoes from the imaging ultrasound transducer and the ablation ultrasound transducer to create a sonogram showing wherein ablation targeting energy from the ablation ultrasound transducer is being delivered.
1 more element
An endovascular carotid body ablation catheter comprising:
- an elongate catheter body;
- and
- an ultrasound ablation focused transducer secured to the catheter body and configured to ablate a carotid body at a distance of 10-20 mm from the transducer when operated at a frequency from 5-10 MHz.
A method of ablating a carotid body, comprising:
- positioning a carotid body ablation catheter proximate a carotid body, the catheter comprising a focused ultrasound ablation transducer;
- and
- operating the focused ultrasound ablation transducer at a frequency from 5-10 MHz and ablating the carotid body from a distance of 10-20 mm.
An intravascular carotid body ablation catheter comprising:
- an elongate catheter body;
- and
- an ultrasound ablation transducer secured to the catheter body, the transducer having a cylindrical configuration with a length dimension, the transducer being curved along the length dimension.
Dependencies are inferred from the claim text.