Tetrahydropyrrolothiazine compounds
AssigneeEli Lilly and Company
InventorsSteven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
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Abstract
The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
Claims7
1-5. (canceled)
A compound which is N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-fluoro-pyridine-2-carboxamide:
- or a pharmaceutically acceptable salt thereof.
A compound which is N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-cyano-pyridine-2-carboxamide:
- or a pharmaceutically acceptable salt thereof.
A compound which is N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-3,5-difluoro-pyridine-2-carboxamide:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.