Colorant compounds derived from genipin or genipin containing materials
AssigneeEcoflora S.A.S.
InventorsEsteban Vargas CANO, Luis Fernando Echeverri Lopez, Juan Fernando Gil Romero, Edwin Andrés Correa Garcés, Sandra Patricia Zapata Porras
Life of this patent
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Abstract
The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products.
Claims37
A colorant composition comprising a polymer of formula 4:
- a geometric isomer thereof, a tautomer thereof, or a salt thereof,
- wherein n is an integer from 2 to 20;
- wherein each A is independently selected from the group consisting of formula 5′A, formula 5′B, formula 5′C, a geometric isomer thereof, a tautomer thereof, a salt thereof, and a combination thereof:
- wherein:
- R1 is hydrogen, methyl, ethyl, propyl, isopropyl, butyl, sec-butyl, isobutyl, or tert-butyl;
- and wherein T1 is hydrogen or a methyl group;
- and T2 is hydrogen or A-T1, wherein A and T1 are defined above;
- wherein the colorant composition is substantially free of a first additional compound selected from the group consisting of formula 2′, formula 3′A, formula 3′B, a geometric isomer thereof, a tautomer thereof, and a salt thereof:
2-4. (canceled)
6-31. (canceled)
A substantially purified polymer of formula 4:
- a geometric isomer thereof, a tautomer thereof, or a salt thereof,
- wherein n is an integer from 2 to 20;
- wherein each A is of formula 5′A (Me), a geometric isomer thereof, a tautomer thereof, or a salt thereof:
- wherein T1 is hydrogen or a methyl group;
- and T2 is hydrogen or A-T1, wherein A and T1 are defined above.
35-39. (canceled)
41-44. (canceled)
46-49. (canceled)
51-53. (canceled)
A colorant composition comprising a polymer of Formula 4:
- a geometric isomer thereof, a tautomer thereof, or a salt thereof,
- wherein n is an integer from 2 to 20;
- wherein each A is independently selected from the group consisting of formula 5A, formula 5B, formula 5C, a geometric isomer thereof, a tautomer thereof, a salt thereof, and a combination thereof:
- wherein:
- R1 is hydrogen, methyl, ethyl, propyl, isopropyl, butyl, sec-butyl, isobutyl, or tert-butyl;
- R2 and R′2 are independently hydrogen, or C1-10 alkyl;
- R3 is hydrogen or COOH;
- and wherein T1 is hydrogen or a methyl group;
- and T2 is hydrogen or A-T1, wherein A and T1 are defined above;
- wherein the colorant composition is substantially free of a first additional compound selected from the group consisting of formula 6, formula 7, formula 8, a geometric isomer thereof, a tautomer thereof, and a salt thereof:
56-58. (canceled)
60-62. (canceled)
64-66. (canceled)
68-71. (canceled)
A method of preparing of a colorant composition comprising
- (a) mixing Genipa americana juice and an amino acid selected from the group consisting of glycine, valine, lysine, methionine, proline, tyrosine, tryptophan, and any combination thereof;
- (b) removing sugar from the mixture of (a);
- and
- (c) isolating a colorant composition from the sugar-free product of (b),
- wherein the intensity of the colorant composition obtained by the method is greater than the intensity of a colorant composition obtained from the mixture of steps (a) without removing sugar.
76-79. (canceled)
81-94. (canceled)
A method of preparing of a purple colorant composition comprising
- (a) isolating mesocarps from Genipa americana fruit;
- (b) preparing a juice extract from the mesocarps;
- (c) mixing the juice extract and glycine;
- (d) after (c), heating the mixture of juice and glycine;
- and
- (e) isolating a purple colorant composition after (d).
(canceled)
A method of preparing of a purple colorant composition comprising
- (a) isolating mesocarps from Genipa americana fruit;
- (b) isolating geniposide from the mesocarps;
- (c) mixing the geniposide and glycine;
- and
- (d) isolating a purple colorant composition after (c).
(canceled)
A method of preparing of a black or green colorant composition comprising
- (a) preparing a juice extract from Genipa americana fruit;
- (c) mixing the juice extract and proline to produce a black colorant or tryptophan to produce a green colorant;
- and
- (e) isolating the black or green colorant composition from (c).
101-113. (canceled)
Dependencies are inferred from the claim text.