Use of Pan-PPAR Agonists for Prevention and Treatment of Huntington's Disease and Tauopathies
AssigneeCornell University
InventorFlint Beal
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Abstract
The present invention provides a therapeutic treatment for a neurodegenerative disease with a pan-PPAR agonist, such as bezafibrate. In particular, the present invention provides that pan-PPAR agonists enhance PPAR related responses in both the central nervous system and peripheral tissues in Huntington's Disease (HD) and tauopathy. Therapeutic compositions comprising one or more pan-PPAR agonist(s), and kit thereof, for treating a neurodegenerative disease or disorder are also provided.
Claims20
A method for treating a neurodegenerative disease comprising administering to a subject in need a therapeutic composition comprising an effective amount of a pan-PPAR agonist.
A therapeutic composition for treating a neurodegenerative disease comprising a Pan-PPAR agonist.
Dependencies are inferred from the claim text.