Insect g-coupled receptors useful as targets for insecticides and compounds and reagents identified using the same

A method of controlling a population of invertebrates, comprising the steps of:

• contacting an invertebrate with a compound that includes at least one of the group consisting of asenapine, amperozide, cis-(Z)-flupenthixol, benztropine, methoiothepin, loxapine, mianserin, clominpramine, amperozide, butaclamol, clozapine, doxepin, and SCH23390 amitriptyline, chlorpromazine chlorprothixene, (±)-butaclamol hydrochloride, doxepin hydrochloride, cis-(Z)-flupenthixol dihydrochloride, methiothepin maleate, mianserin hydrochloride, niclosamide, piceatannol, and resveratrol.

A method for screening, comprising the steps of:

• expressing a polynucleotide having at least 90 percent homology to at least one of SEQ ID. NO. 1 and SEQ ID. NO. 3;
• and
• contacting cells that express said polynucleotide with at least one exogenous compound, wherein said polynucleotide is not expressed in its native host.