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US 2014/0350057 A1Published application
Chemical compound useful as intermediate for preparing a catechol-o-methyltransferase inhibitor
AssigneeBial - Portela & Ca, S.A.
InventorsDomenico Russo, Laszlo Erno Kiss, Jorge Bruno Reis Wahnon, David Alexander Learmonth, Tibor Eszenyi, Axel Zimmermann, Bjoern Schlummer, Michael Kreis, Klaus Reiter
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Abstract
There is disclosed a methylated intermediate which may be demethylated to provide an inhibitor of catechol-O-methyltransferase useful in the treatment of Parkinson's disease. Also disclosed are methods of making and using said intermediate.
Claims37
A compound of the formula (I)
- or a salt thereof.
A pharmaceutical composition in unit dosage form for oral administration which comprises a compound of the formula (II)
- in microparticulate form in a pharmaceutically acceptable carrier therefore.
Dependencies are inferred from the claim text.