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US 2014/0350054 A1Published application
Small-volume oral transmucosal dosage forms
AssigneeAcelRx Pharmaceuticals, Inc.
InventorsPamela Palmer, Thomas Schreck, Stelios Tzannis, Lawrence Hamel, Andrew I. Poutiatine
Life of this patent
Estimating the term…
Abstract
Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
Claims20
1-170. (canceled)
A dosage form for oral transmucosal administration to a subject, comprising:
- from about 0.25 micrograms to about 200 micrograms sufentanil, wherein said dosage form is bioadhesive and has a volume of less than 30 microliters or a mass of less than 30 mg.
A dosage form for oral transmucosal administration to a subject, comprising:
- a bioadhesive dosage form for delivery of sufentanil with a volume of less than 30 microliters or a mass of less than 30 mg wherein the administration of the dosage form to the subject results in a dose-normalized Cmax of about 2.72+/−0.84 pg/mL per mcg of sufentanil dosed.
Dependencies are inferred from the claim text.