Methods and pharmaceutical compositions for the treatment of darier disease
AssigneesInserm (Institut National De La Sante Et De La Recherche Medicale), Universite Paris Descartes
InventorsAlain Hovnanian, Magali Savignac
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Abstract
The present invention relates to methods and pharmaceutical compositions for the treatment of Darier disease. More particularly, the present invention relates to an agent that is able to restore E-cadherin trafficking in DK and the formation of adherens junctions for use in a method for treating patients with Darier disease. In particular, the present invention relates to an agent selected from the group consisting of molecular, chemical and pharmacologic chaperones for use in a method for treating patients with Darier disease.
Claims5
A method for treating a patient with Darier disease comprising administering to said patient an agent that is able to restore E-cadherin trafficking in Darier keratinocytes (DK) and formation of adherens junctions, wherein said agent is selected from the group consisting of molecular, chemical and pharmacologic chaperones.
Dependencies are inferred from the claim text.