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US 2014/0350030 A1Published application
Bicarbocyclic and tricarbocyclic ethynyl derivatives and uses of same
AssigneeH. Lundbeck A/S
InventorsDario Doller, Guiying Li
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Abstract
The present invention provides compounds of formula (I): where R1, R2, X, Y and n are as described herein, and pharmaceutical compositions, uses and methods comprising same.
Claims15
1) A compound of formula (I):
- wherein:
- R1 and R2 are independently aryl, heteroaryl, heterocyclyl which is optionally mono-, di-, or tri-substituted independently with alkyl, halogen, hydroxy, cyano, amino, alkylamino, dialkylamino, acyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, ketocycloalkyl, alkoxy, hydroxylalkyl, trifluoromethyl;
- and
- When n=0 and 1, X and Y are H;
- and
- When n=1, both X and Y are bonds that are linked to —CH2— to form a tricyclic adamantyl core;
3 more elements
Dependencies are inferred from the claim text.