Use of fluorine-containing water soluble platinum complex in preparing drugs for prevention and treatment of cancers

A method for treating or preventing cancer in a patient, comprising administering a therapeutical composition containing a water soluble fluorine-containing platinum complex of formula (I):

• Wherein:
• X and Y are ligand. X and Y are same or independently chosen from NH3, isopropylamine, or X and Y together form a 1,2-cyclohaxanediamine chosen from trans -(1R,2 R)-cyclohexanediamine, trans-(1S,2S)-cyclohexanediamine, cis-(1R,2 S)-cyclohexanediamine, cis-(1S -2R)-cyclohexanediamine, trans-meso-1,2-cyclohexanediamine, cis-meso-1,2-cyclohexanediamine;
• n is an integer from 1 to 6;
• R is chosen from
• wherein the monosaccaride represents the isomer of—or—or mixture of both;
• The cancer is selected from the group consisting of human non-small cell lung cancer, human prostate cancer, human breast cancer, human ovarian cancer, human leukemia cancer or human colorectal cancer.

A method for treating or preventing cancer in a patient, comprising administering a therapeutical composition containing a water soluble fluorine-containing platinum complex of formula (I):

• Wherein:
• X and Y are ligand. X and Y are same or independently chosen from NH3, isopropylamine, or X and Y together form a 1,2-cyclohaxanediamine chosen from trans-(1R,2 R)-cyclohexanediamine, trans-(1S,2S)-cyclohexanediamine, cis-(1R,2 S)-cyclohexanediamine, cis-(1S-2R)-cyclohexanediamine, trans-meso-1,2-cyclohexanediamine, cis-meso-1,2-cyclohexanediamine;
• n is an integer from 1 to 6;
• R is chosen from
• wherein the monosaccaride represents the isomer of—or—or mixture of both;
• with one or more further chemotherapeutic agents chosen from the group consisting of Cisplatin, Transplatin, trans-diaminetetrachloroplatinum (IV), Carboplatin, Oxaliplatin, 5-FU, Deoxifluridine, Tegafur, Gemcitabine, Capecitabine, Clofarabine, Temozolomide, Lonafarnib, Erlotinib, Sorafenib, Sunitinib, Imatinib, Erlotinib, Bortezomib, Gimatecan, Vinblastine, Vinorelbine, Folinic Acid, Doxorubicin, Paclitaxel, Docetaxel and their diravertives, Tamoxifen, Raloxifene, Spiramycin, Irinotecan. The cancer is selected from the group consisting of human non-small cell lung cancer, human prostate cancer, human breast cancer, human ovarian cancer, human leukemia cancer or human colorectal cancer.