Hyaluronic acid containing compositions for treatment of wounds, scars, post-surgical adhesion formation
AssigneePergamum AB
InventorsMargit Mahlapuu, Mattias Münnich, Veronika Sjöstrand
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Abstract
The present invention relates to pharmaceutical compositions enhancing the therapeutic effect of biologically active peptides, especially peptides derived from human lactoferrin. The compositions are useful for the treatment and/or prevention of wounds, scars, and post surgical adhesions.
Claims12
A pharmaceutical composition comprising
- i) one or more biologically active peptides comprising the amino acid sequence Phe-X1-X2-X3-X4-X5-X6-X7-Lys-Val-Arg (SEQ ID NO:1),
- wherein amino acid X1 is Gln or Ala, amino acid X2 is Trp or Leu, amino acid X3 is Gln, Ala, Orn, Nle or Lys, amino acid X4 is Arg, Ala or Lys, amino acid X5 is Asn, Ala, Orn or Nle, amino acid X6 is Met, Ala or Leu, amino acid X7 is Arg, Ala or Lys, and
- ii) a high molecular weight hyaluronic acid or a pharmaceutical acceptable salt of a high molecular weight hyaluronic acid.
Use of i) a biologically active peptide derived from lactoferrin comprising the amino acid sequence Phe-X1-X2-X3-X4-X5-X6-X7-Lys-Val-Arg (SEQ ID NO:1), and ii) a high molecular weight hyaluronic acid for the manufacture of a pharmaceutical composition for the treatment and/or prevention of wounds, scars, and post surgical adhesions.
Dependencies are inferred from the claim text.