Treatment of Chronic Constipation
AssigneesForest Laboratories Holdings Limited, Ironwood Pharmaceuticals, Inc.
InventorsJeffrey Johnston, Angelika Fretzen, Steven Witowski, Alfredo Grossi, Hong Zhao, Bernard Joseph Lavins, Mahendra Dedhiya, Harvey Schneier
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Abstract
The invention provides methods for treating a patient with chronic constipation by administering a therapeutically effective dose of linaclotide.
Claims21
1-82. (canceled)
A method of treating a patient with chronic constipation, comprising administering a therapeutically effective dose of linaclotide once a day.
A method of treating a patient with chronic constipation, comprising administering a therapeutically effective dose of a GC-C agonist and wherein discontinuing the administration of a therapeutically effective dose of a GC-C does not produce a chronic constipation symptom rebound for said patient.
A method of treating a patient with chronic constipation, comprising administering a therapeutically effective dose of a GC-C agonist, wherein the GC-C agonist produces a rapid or sustained relief of symptoms associated with chronic constipation
Dependencies are inferred from the claim text.