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US 2014/0349924 A1Published application
Stable Non-Aqueous Pharmaceutical Compositions
AssigneeNovo Nordisk A/S
InventorsSimon Bjerregaard Jensen, Svend Havelund, Florian A. Foeger
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Abstract
The present invention relates to shelf stable non-aqueous pharmaceutical compositions, and to the use thereof in methods of treating diabetes and hyperglycaemia.
Claims10
Pharmaceutical non-aqueous composition comprising a mixture of
- a) a dehydrated therapeutically active polypeptide comprising 10-100 amino acids, and
- b) at least one semi-polar protic organic solvent
- which polypeptide has been dehydrated at a target pH which is at least 1 pH unit from the pI of the polypeptide in aqueous solution.
Dependencies are inferred from the claim text.