Garcinia buchananii baker compounds, compositions and related methods
OwnerOnesmo B. Balemba, Thomas Hofmann +7inventors
InventorsOnesmo B. Balemba, Thomas Hofmann, Sofie Pasilis, Gary M. Mawe, Stuart M. Brierley, Gemma Mazzuoli, Timo Stark, Michael Schemann, Dagmar Kruger
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Abstract
Embodiments of the present disclosure related to compounds and compositions derived from G. buchananii baker and methods thereof.
Claims36
A composition comprising an isolated compound with a structure as defined in formula 11
- wherein A, X, Y and Z are each independently H, OH, halogen, CN, amine, imine or imide, and wherein R and T are bonds to other molecules with formula 11.
A composition comprising a fraction of an extract of a component of G. buchananii wherein the extract is enriched in a compound having a formula selected from the group consisting of
A composition comprising a fraction of an extract of a component of G. buchananii wherein the extract is enriched in a compound with antioxidant properties.
A method of treating constipation in a subject in need thereof comprising administering a fraction of a component of G. buchananii wherein the fraction comprises at least one compound present in the PTLC2 or M6 fractions.
Dependencies are inferred from the claim text.