Pharmaceutical compositions of lurasidone
AssigneeCadila Healthcare Limited
InventorsBrij Khera, Aman Trehan, Pankaj Ramanbhai Patel
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Abstract
The present invention relates to pharmaceutical compositions of lurasidone or salts thereof. In particular, the invention relates to pharmaceutical compositions of lurasidone or salts thereof with one or more water-insoluble pharmaceutical excipients. The invention also relates to processes for the preparation of such compositions and use thereof for treatment of schizophrenia, bipolar disorders or senile dementia.
Claims17
A pharmaceutical composition comprising lurasidone or salts thereof and one or more pharmaceutical excipients, wherein the composition is free of water-soluble excipients.
A pharmaceutical composition comprising lurasidone or salts thereof and one or more pharmaceutical excipients, wherein the composition is free of water-soluble binders.
A pharmaceutical composition comprising lurasidone or salts thereof and one or more pharmaceutical excipients, wherein the composition is free of pregelatinized starch.
A pharmaceutical composition comprising—
- (a) about 20% to about 45% by weight of lurasidone or salts thereof;
- (b) about 10% to about 80% by weight of one or more water-insoluble diluent/s;
- (c) about 1% to about 55% by weight of one or more water-insoluble binder/s;
- (d) about 1% to about 10% by weight of one or more water-insoluble disintegrating agents/s;
- and
- (e) about 0.5% to about 5% by weight of one or more water-insoluble lubricant/s.
Dependencies are inferred from the claim text.