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US 2014/0296539 A1Published application
Compound and Asymmetric Synthesis Reaction
AssigneeMicrobial Chemistry Research Foundation
InventorsMasakatsu SHIBASAKI, Naoya KUMAGAI
Life of this patent
Estimating the term…
Abstract
A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
Claims7
A compound represented by the following General Formula (1):
- where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
A compound represented by the following General Formula (2):
- where R1 represents a protective group for a hydroxyl group or a hydrogen atom, R2 represents a methyl group or an ethyl group, and R3 represents a protective group for a hydroxyl group or a hydrogen atom.
A compound represented by the following General Formula (3):
- where R1 represents a protective group for a hydroxyl group or a hydrogen atom, R2 represents a methyl group or an ethyl group, R3 represents a protective group for a hydroxyl group or a hydrogen atom, R4 represents a methyl group or an ethyl group, and X− represents a monovalent anion.
An asymmetric synthesis reaction, comprising:
- allowing a compound represented by the following General Formula (4) and a compound represented by the following General Formula (5) to react with each other in the presence of a chiral silver complex obtained from a silver compound and a compound represented by the following General Formula (A) to thereby obtain a compound represented by the following General Formula (6):
- where Ra each independently represents a hydrogen atom, an alkyl group, an alkoxy group, an alkenyl group, an aryl group, an arylalkyl group, an arylalkenyl group, a non-aromatic heterocyclic ring, or an aromatic heterocyclic ring, m is an integer of 1 or 2;
- when m is 2, two Ra may be bonded together to form a ring structure;
- and Ar represents an aryl group which may have a substituent,
- where in General Formulas (4) to (6), R11 represents a hydrogen atom or a substituent, R12 represents a methyl group or an ethyl group, and n is an integer of 1 to 3.
2 more elements
An asymmetric synthesis reaction, comprising:
- allowing a compound represented by the following General Formula (4) and a compound represented by the following General Formula (5) to react with each other in the presence of a chiral silver complex obtained from a silver compound and a compound represented by the following General Formula (B) to thereby obtain a compound represented by the following General Formula (7):
- where Ra each independently represents a hydrogen atom, an alkyl group, an alkoxy group, an alkenyl group, an aryl group, an arylalkyl group, an arylalkenyl group, a non-aromatic heterocyclic ring, or an aromatic heterocyclic ring, m is an integer of 1 or 2;
- when m is 2, two Ra may be bonded together to form a ring structure;
- and Ar represents an aryl group which may have a substituent,
- where in General Formulas (4) and (7), R11 represents a hydrogen atom or a substituent, and in General Formulas (5) and (7), R12 represents a methyl group or an ethyl group, and n is an integer of 1 to 3.
2 more elements
Dependencies are inferred from the claim text.