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US 2014/0278136 A1Published application
Rapid determination of microbial growth and antimicrobial susceptibility
AssigneeAccelerate Diagnostics, Inc.
InventorsAlena Shamsheyeva, David C. Howson, Steven W. Metzger
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Abstract
This disclosure is related to systems and methods for rapid determination of microorganism growth and antimicrobial agent susceptibility and/or resistance.
Claims37
A method, comprising:
- determining, by a computer-based system configured to analyze microorganism information and comprising a processor, a tangible memory, and an interface, a first value associated with an attribute of a microorganism, based on first information from a microorganism detection device;
- determining, by the computer-based system, a second value associated with the attribute of the microorganism, based on second information from the microorganism detection device determining, by the compute-based system, a growth rate associated with the first value and the second value;
- and
- comparing, by the computer-based system, the growth rate to a control growth rate.
1 more element
A method, comprising:
- determining, by a computer-based system configured to analyze microorganism information and comprising a processor, a tangible memory, and an interface, a first value corresponding to a growth rate of a microorganism, based on information from a microorganism detection device, in response to subjecting a microorganism to at least one of a first event and a first condition;
- obtaining, by the computer-based system, a second value corresponding to a growth rate of a reference microorganism;
- determining, by the computer-based system, a proportional relationship between the first value to second value.
A method comprising:
- contacting a sample comprising a viable microorganism with a sample chamber;
- introducing a gel medium into the sample chamber, wherein the gel medium is in contact with the microorganism following introduction into the sample chamber;
- immobilizing the microorganism in the sample chamber to produce an immobilized microorganism;
- incubating the immobilized microorganism for a first time period, wherein the first time period comprises a first time and a second time;
- detecting an attribute of the immobilized microorganism with a computer-based system configured to detect individual immobilized microorganism cells.
2 more elements
Dependencies are inferred from the claim text.