Implantable repair device
AssigneeOrthox Limited
InventorNicholas Skaer
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Abstract
An implantable repair device for the repair, augmentation or replacement of tissue, uses silk fibroin and has a smooth surface and a porous surface. The smooth surface has a measured Sa value of less than approximately 0.1 μm when using Atomic Force Microscopy when samples of the repair device are fully hydrated by imaging through fluid in peak force tapping mode. A method of preparing such an implantable repair device includes preparing a gel from a fibroin solution in a mould, preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel, and creating at least a porous surface on the device, wherein a portion of the mould is adapted to provide at least one smooth surface.
Claims27
An implantable repair device for the repair, augmentation or replacement of tissue, the device comprising silk fibroin and wherein the device comprises a smooth surface and a porous surface.
A method of preparing an implantable repair device or a portion or layer of such a device for the repair, augmentation or replacement of tissues, the method comprising the steps of:
- preparing a gel from a fibroin solution in a mould;
- preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel;
- and creating a porous surface on said device, wherein in preparing the gel from the fibroin solution, a portion of the mould is adapted to provide at least one smooth surface.
Dependencies are inferred from the claim text.