Injectable hydrogels
AssigneeSt. Jude Medical Systems AB
InventorsLisa MELLIN, Niklas BORG, Martina KÄLLROT
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Abstract
Described herein are methods of forming hydrogels comprising combining (a) a water-soluble polymer comprising thiol groups, and (b) a water-soluble metal salt in an aqueous solution. The hydrogels form rapidly. Hydrogels and related methods, uses, and products also are described.
Claims22
A method for producing a hydrogel comprising combining
- (a) a water-soluble polymer comprising thiol groups, and
- (b) a water-soluble metal salt
- in an aqueous solution, thereby forming a hydrogel.
A hydrogel comprising:
- (a) a polymer comprising a polymer backbone and, optionally, substituents, branches, or both, wherein the polymer comprises thiol groups attached to one or more of the backbone, substituents, or branches;
- and
- (b) metal atoms to which the thiol groups are bound,
- wherein the hydrogel does not contain gold nanoparticles.
A kit for forming a hydrogel comprising:
- (a) first component comprising a water-soluble polymer;
- and
- (b) a second component comprising a water-soluble metal salt.
A vascular closure device comprising a housing, wherein the housing comprises a first compartment and a second compartment, wherein the first compartment holds a water-soluble polymer comprising thiol groups and the second compartment holds a water-soluble metal salt.
Dependencies are inferred from the claim text.