Methods of embolic filtering
AssigneeInsera Therapeutics, Inc.
InventorsVallabh Janardhan, Vikram Janardhan
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Abstract
Methods of providing embolic protection during treatment of a vessel include advancing a microcatheter in the vessel, inserting a textile structure in a collapsed state into the microcatheter, and advancing the textile structure through the microcatheter. The methods may include, after advancing the textile structure and retracting the microcatheter to unsheathe a self-expanding bulb of the textile structure from the microcatheter, thereby allowing the self-expanding bulb to self-expand from the collapsed state to an expanded state. The methods may include performing a vascular procedure. In the expanded state, the self-expanding bulb may filter emboli released during performing the vascular procedure.
Claims20
A method of providing embolic protection during treatment of a vessel, the method comprising:
- advancing a microcatheter in the vessel, wherein advancing the microcatheter includes crossing a thrombus with a distal end of the microcatheter;
- inserting a textile structure in a collapsed state into the microcatheter, the textile structure comprising a plurality of self-expanding bulbs and a plurality of necks,
- wherein the plurality of self-expanding bulbs comprises five to twenty self-expanding bulbs, each of the plurality of self expanding bulbs having a spherical shape or an oblong shape,
- wherein pairs of the self-expanding bulbs are spaced by a neck of the plurality of necks;
- advancing the textile structure through the microcatheter proximate to the distal end of the microcatheter, wherein advancing the textile structure includes crossing the thrombus with a distal-most bulb of the plurality of self-expanding bulbs;
- after advancing the textile structure, retracting the microcatheter to unsheathe a length of the textile structure, wherein retracting the microcatheter to unsheathe the length of the textile structure comprises:
- unsheathing at least the distal-most bulb of the plurality of self-expanding bulbs from the microcatheter, and
- self-expanding at least the distal-most bulb of the plurality of self-expanding bulbs from the collapsed state to an expanded state;
- and
- removing the thrombus from the vessel,
- wherein, in the expanded state, the distal-most bulb:
- apposes sidewalls of the vessel, and
- filters emboli released during the removing the thrombus from the vessel.
A method of providing embolic protection during treatment of a vessel, the method comprising:
- advancing a microcatheter in the vessel;
- inserting a textile structure in a collapsed state into the microcatheter, the textile structure comprising a plurality of self-expanding bulbs and a plurality of necks, pairs of the self-expanding bulbs spaced by a neck of the plurality of necks;
- advancing the textile structure through the microcatheter proximate to a distal end of the microcatheter;
- after advancing the textile structure, retracting the microcatheter to unsheathe a length of the textile structure, wherein retracting the microcatheter to unsheathe the length of the textile structure comprises:
- unsheathing at least a distal-most bulb of the plurality of self-expanding bulbs from the microcatheter, and
- self-expanding at least the distal-most bulb of the plurality of self-expanding bulbs from the collapsed state to an expanded state;
- and
- performing a vascular procedure, wherein performing the vascular procedure comprises using a vascular device different than the textile structure,
- wherein, in the expanded state, the distal-most bulb of the plurality of self-expanding bulbs filters emboli released during performing the vascular procedure,
- torsionally rasping the textile structure, the distal-most bulb of the plurality of self-expanding bulbs providing a distal anchor for the torsionally rasping.
(canceled)
A method of providing embolic protection during treatment of a vessel, the method comprising:
- advancing a microcatheter in the vessel;
- inserting a woven textile structure in a collapsed state into the microcatheter;
- advancing the textile structure through the microcatheter proximate to a distal end of the microcatheter;
- after advancing the textile structure, retracting the microcatheter to unsheathe a self-expanding bulb from the microcatheter, thereby allowing the self-expanding bulb to self-expand from the collapsed state to an expanded state;
- and
- performing a vascular procedure, wherein, in the expanded state, the self-expanding bulb filters emboli released during performing the vascular procedure,
- at least one of after and during performing the vascular procedure, further retracting the microcatheter, wherein further retracting the microcatheter comprises unsheathing other self-expanding bulbs and self-expanding the other self-expanding bulbs from the collapsed state to an expanded state, the other self-expanding bulbs in the expanded state entrapping residual emboli.
(canceled)
Dependencies are inferred from the claim text.