Length and diameter adjustable balloon catheter for drug delivery

An adjustable balloon catheter comprising:

• an inner tubular member having a proximal end portion, a distal end portion, and a length therebetween, the inner tubular member further having an inflation lumen defined therein;
• an expandable member coupled to the distal end portion of the inner tubular member and having an inner chamber defined therein in fluid communication with the inflation lumen, the expandable member transitionable between a deflated configuration and an inflated configuration, the expandable member further having an exterior surface along a working length thereof, the exterior surface defining at least a portion of a compartment along the working length of the expandable member when in the inflated configuration, the exterior surface further having a beneficial agent release structure associated therewith in communication with the compartment;
• and
• an outer tubular member movable relative to the inner tubular member, the outer tubular member including a distal end, the outer tubular member being moveable between an extended position disposed over the expandable member and a retracted position proximal to the extended position, the outer tubular member being selectively positioned between the extended position and the retracted position to define an exposed length of the working length of the expandable member.

A method of delivering a beneficial agent, comprising:

• providing an adjustable balloon catheter including:
• an inner tubular member having a proximal end portion, a distal end portion, and a length therebetween, the inner tubular member further having an inflation lumen and a fluid lumen defined therein,
• an expandable member coupled to the distal end portion of the inner tubular member and having an inner chamber defined therein in fluid communication with the inflation lumen, the expandable member transitionable between a deflated configuration and an inflated configuration, the expandable member further having an exterior surface along a working length thereof, the exterior surface having at least one pore structure defined therein in fluid communication with the fluid lumen, and
• an outer tubular member movable relative to the inner tubular member, the outer tubular member including a distal end, the outer tubular member being moveable between an extended position disposed over the expandable member and a retracted position proximal to the extended position, the outer tubular member being selectively positioned between the extended position and the retracted position to define an exposed length of the working length of the expandable member;
• and
• retracting the outer tubular member in a proximal direction to define the exposed length of the working length of the expandable member;
• inflating the exposed length of the expandable member to the inflated configuration;
• releasing beneficial agent from the at least one pore structure;
• and
• deflating the expandable member to the deflated configuration.

A method of delivering a beneficial agent, comprising:

• providing an adjustable balloon catheter including:
• an inner tubular member having a proximal end portion, a distal end portion, and a length therebetween, the inner tubular member further having an inflation lumen and a fluid lumen defined therein;
• an expandable member coupled to the distal end portion of the inner tubular member and having an inner chamber defined therein in fluid communication with the inflation lumen, the expandable member transitionable between a deflated configuration and an inflated configuration, the expandable member further having an exterior surface along a working length thereof, the exterior surface defining at least one a portion of a compartment along the working length of the expandable member when in the inflated configuration, the exterior surface further having a beneficial agent release structure associated therewith in communication with the at least one compartment;
• and
• an outer tubular member movable relative to the inner tubular member, the outer tubular member including a distal end, the outer tubular member being moveable between an extended position disposed over the expandable member and a retracted position proximal to the extended position, the outer tubular member being selectively positioned between the extended position and the retracted position to define an exposed length of the working length of the expandable member,
• retracting the outer tubular member in a proximal direction to define the exposed length of the working length of the expandable member;
• inflating the exposed length of the expandable member to the inflated configuration with the compartment along the exposed length;
• releasing beneficial agent from the beneficial agent release structure into the compartment;
• and
• deflating the expandable member to the deflated configuration.