Transdermal methylphenidate compositions with acrylic block copolymers
AssigneeNoven Pharmaceuticals, Inc.
InventorsJun Liao, Puchun Liu, Steven Dinh
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Abstract
Described herein are transdermal compositions comprising methylphenidate in a polymer matrix comprising a non-reactive random acrylic polymer and an acrylic block copolymer. Method of making such compositions, and therapeutic methods using them also are disclosed.
Claims17
A composition for the transdermal delivery of methylphenidate in the form of a flexible finite system for topical application, comprising a polymer matrix comprising methylphenidate or a pharmaceutically acceptable salt or prodrug thereof, wherein the polymer matrix comprises a non-reactive random acrylic polymer and an acrylic block copolymer.
A method of manufacturing a composition for the transdermal delivery of methylphenidate in the form of a flexible finite system for topical application, comprising forming a polymer matrix blend comprising a non-reactive random acrylic polymer, an acrylic block copolymer, and methylphenidate or pharmaceutically acceptable salt or prodrug thereof in a solvent, applying the polymer matrix blend to a support layer, and removing any remaining solvent.
Dependencies are inferred from the claim text.