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US 2014/0276482 A1Published application
Systems for Sustained Intraocular Delivery of Low Solubility Compounds from a Port Delivery System Implant
AssigneeForSight Vision4, Inc.
InventorsIrina Astafieva, Judit Horvath, Kathleen Cogan Farinas, Blaine Bueche, Signe Erickson
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Abstract
Therapeutic agent delivery formulations for the sustained release of therapeutic agents from a Port Delivery System (PDS) implant is described in this application.
Claims25
A therapeutic agent delivery system comprising a therapeutic device having a reservoir chamber coupled to a porous structure for controlled release of a therapeutic agent in the vitreous of the eye and a formulation comprising a therapeutic agent and one or more formulation agents, wherein the formulation is contained in the reservoir of the therapeutic device;
- and the controlled release of the therapeutic agent and formulation agents from the reservoir through the porous structure increases the half-life of the therapeutic agent in the vitreous.
-46. (canceled)
Dependencies are inferred from the claim text.