Transdermal drug delivery system with overlay
AssigneeNoven Pharmaceuticals, Inc.
InventorsViet Nguyen, Puchun Liu, Steven Dinh
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Abstract
Transdermal drug delivery systems comprising a drug-containing layer, a backing layer, and an occlusive overlay layer extending beyond the perimeter of the backing layer by 3 to 6 mm in all directions are described. The systems achieve increased drug delivery over an extended time period.
Claims14
A transdermal drug delivery system comprising a drug-containing polymer matrix layer, a backing layer co-terminus with the polymer matrix layer, and an occlusive overlay layer extending beyond the perimeter of the polymer matrix layer and backing layer by 3 to 6 mm in all directions.
A method of enhancing transdermal drug delivery of a drug from a transdermal drug delivery system comprising a drug-containing polymer matrix layer and a backing layer co-terminus with the polymer matrix layer, comprising
- providing a transdermal drug delivery system comprising a drug-containing polymer matrix layer and a backing layer co-terminus with the polymer matrix layer with an occlusive overlay layer extending beyond the perimeter of the polymer matrix layer and backing layer by 3 to 6 mm in all directions, and
- administering said system to a subject in need thereof,
- wherein the method achieves increased drug delivery as compared to drug delivery from a corresponding system that does not include the overlay layer.
A method of manufacturing a transdermal drug delivery system for enhanced transdermal drug delivery, comprising
- providing a transdermal drug delivery system comprising a drug-containing polymer matrix layer and a backing layer co-terminus with the polymer matrix layer with an occlusive overlay layer that extends beyond the perimeter of the polymer matrix layer and backing layer by 3 to 6 mm in all directions.
Dependencies are inferred from the claim text.