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US 2014/0276312 A1Published application
Combinatorial therapy for treatment of osteoarthritis of the knee
AssigneeRMG Rehabilitation Management Group, LP
InventorsMark Wayne LEE, John Samuel VICK
Life of this patent
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Abstract
Embodiments of the present invention generally relate to methods of knee rehabilitation. Embodiments generally include the use of viscosupplementation delivered intra-articularly in conjunction with rehabilitative therapy and an unloading knee brace. The injection of the viscosupplementation is guided such that the entire dose is delivered to the joint and can flow tricompartmentally.
Claims20
A method of treatment for a joint comprising:
- determining a site of injection in a knee of a patient using flow determination imaging;
- injecting a volume of a medium to high molecular weight hyaluronate composition into the selected site of injection, wherein the high molecular weight hyaluronate composition flows tricompartmentally;
- providing one or more rehabilitation routines to the patient, wherein the rehabilitation routines increase blood flow and strengthen muscles proximate to the joint;
- and
- supporting the knee using a weight bearing support at least during one of the one or more rehabilitation routines.
2 more elements
A method for treating osteoarthritis in a patient comprising:
- providing an unloading knee brace for supporting a knee of a patient such that at least a portion of the weight born by the knee is supported by the brace;
- determining an injection site in the knee of the patient, the injection site selected to allow for tricompartmental flow;
- injecting a volume of a hyaluronate composition into the injection site with fluoroscopic guidance, the hyaluronate composition comprising:
- a high molecular weight hyaluronate;
- and
- a diluent, wherein the volume of the diluent and the high molecular weight hyaluronate is at least 2.5 ml;
- and
- providing one or more rehabilitative exercise sessions to the patient.
5 more elements
A method for treatment of a joint comprising:
- determining whether tricompartmental flow exists in an affected knee joint of a patient;
- affixing a weight bearing support to the affected knee joint of the patient, wherein the affected knee joint has one or more degeneration sites;
- if tricompartmental flow exists, determining one or more sites of injection in the affected knee joint which allow tricompartmental flow and are proximate to one or more degeneration sites in the affected knee joint, wherein the sites of injection are determined using flow determination imaging;
- injecting a hyaluronate composition comprising hyaluronate with a molecular weight of greater than 700 kD into the one or more sites of injection using fluoroscopic guidance, the injection delivered from three to five times with a separation between injections of seven to ten days;
- and
- providing one or more physical therapy rehabilitative routines to the patient before each injection, the routines designed to strengthen a muscle group which reduces pressure on at least one of the one or more degeneration sites.
3 more elements
Dependencies are inferred from the claim text.