Coated Surgical Mesh, and Corresponding Systems and Methods
AssigneeCell and Molecular Tissue Engineering, LLC
InventorsUlrike W. Klueh, Donald L. Kreutzer
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Abstract
Disclosed herein is a surgical mesh with a layer of dehydrated basement membrane formed thereon. Methods of making and using the mesh also are disclosed.
Claims14
A surgical mesh with a layer of dehydrated basement membrane formed thereon.
A method comprising:
- obtaining an implantable device comprising a surgical mesh,
- placing basement membrane in the form of a liquid or gel on the implantable device to form at least one of a sleeve and a collar on the device, and
- dehydrating the basement membrane on the implantable device.
A method of promoting the biocompatibility of a surgical mesh with biological tissue, comprising forming an extracellular matrix coating around a surgical mesh, the coating comprising dehydrated extracellular matrix which is rehydrated after implantation, the extracellular matrix having cells and/or factors attached thereto using fibronectin.
Dependencies are inferred from the claim text.