US 2014/0275709 A1 · METHODS AND SYSTEMS FOR DETERMINING THE DISTRIBUTION OF RADIATION DOSE AND RESPONSE

Abstract

A system, method and computer program product to determine radiation dose from radionuclides used to treat a patient in need thereof. The present invention allows users to visualize and understand the impact of radionuclide choice, distribution of activity in the cell, distribution of activity among the cells, cell dimensions, cell separation distance, cluster size, and radiobiological response parameters on the capacity to kill populations of cells. All of these parameters can play a substantial role in determining the surviving fraction of cells. Accordingly, this system, method and computer program product can assist in designing treatment plans for therapeutic radiopharmaceuticals suited to individual needs.

Claims18

Dependent claims

A computing-implemented method of determining a dose of radiation for a patient for radiation therapy treatment planning, the method comprising:

receiving, by a computing device, one or more features associated with a dose of radiation;
displaying, by the computing device, a menu of one or more of the features associated with the dose of radiation, wherein each feature corresponds to a category of information;
receiving, by the computing device from the user, a selection of one or more feature from the menu of features;
and
for each selected feature:
receiving, by the computing device, information pertaining to the selected feature,
determining, by the computing device radiation data for a radionuclide,
determining, by the computing device a radiobiological parameter,
determining, by the computing device a target volume and source volume,
determining, by the computing device a cell geometry, and
determining, by the computing device, a dose of radiation based upon the selected features.

8 more elements

A radiation therapy planning system configured to determine a dose of radiation for a patient for radiation therapy treatment planning, the system comprising:

a computing device;
and
a computer-readable storage medium in communication with the computing device, wherein the computer-readable storage medium comprises one or more programming instructions that, when executed, causes the computing device to:
receive, one or more features associated with a dose of radiation from a computing source;
display, a menu of one or more of the features associated with the dose of radiation, wherein each feature corresponds to a category of information;
receive, a selection of one or more feature from the menu of features;
and
for each selected feature:
receive information pertaining to the selected feature,
determine radiation data for a radionuclide;
determine a radiobiological parameter;
determine a target volume and source volume;
determine a cell geometry;
and
determine a dose of radiation based upon the selected features.

12 more elements

Dependencies are inferred from the claim text.

Methods and systems for determining the distribution of radiation dose and response

Life of this patent

Methods and systems for determining the distribution of radiation dose and response

Life of this patent

Abstract

Claims18