Novel compounds
AssigneeAvanti Polar Lipids, Inc.
InventorsStephen W BURGESS, Walter A. SHAW, Shengrong LI
Life of this patent
Estimating the term…
Loading patent…
AssigneeAvanti Polar Lipids, Inc.
InventorsStephen W BURGESS, Walter A. SHAW, Shengrong LI
Estimating the term…
Disclosed are compounds of the general formula I and II (as further defined herein) are useful in the production of inhibitors of sphingolipid synthesis the production of sphingolipids. Suitable sphingolipids, include, but not limited to, sphingosine and compounds incorporating sphingosine or that may use sphingosine as an intermediate or a starting material in their synthesis (including, but not limited to, sphingosine-1-P, ceramide, gangliosides and sphingomyelin). In one contemplated use, compounds of the general formula I and II are useful in the production of sphingosine. In another contemplated use, compounds of the general formula I and II are useful in the production of a sphingofugin. Methods of manufacturing each of the above compounds are also provided.
A compound of the general formula I:
The compound of claim 9, wherein R1 contains from 1 to 6 substitutions.
The compound of claim 10, wherein the substituents on R1 are independently selected from —OH, —NH2, —N3 or ═O
A compound of the general formula II:
Dependencies are inferred from the claim text.