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US 2014/0275586 A1Published application
Thioesterases and cells for production of tailored oils
AssigneeSolazyme, Inc.
InventorsGeorge N. Rudenko, Jason Casolari, Scott Franklin
Life of this patent
Estimating the term…
Abstract
The invention features plant acyl-ACP thioesterase genes of the FatB class and proteins encoded by these genes. The genes are useful for constructing recombinant host cells having altered fatty acid profiles. Oleaginous microalga host cells with the new genes or previously identified FatB genes are disclosed. The microalgae cells produce triglycerides with useful fatty acid profiles.
Claims11
An isolated nucleic acid having at least 80% sequence identity to any of SEQ ID NOS:
- 2, 3, 5, 6, 8, 9, 11, 12, 14, 15, 17, 18, 20, 21, 23, 24, 26, 27, 29, 30, 32, 33, 35, 36, 38, 39, 41, 42, 44, 45, 47, 48, 50, 51, 53, 54, 56, 57, 59, 60, 62, 63, 65, 66, 68, 69, 71, 72, 74, 76, or 78 or any equivalent sequences by virtue of the degeneracy of the genetic code.
An isolated nucleic acid sequence encoding a protein having at least 80% sequence identity to any of SEQ ID NOS:
- 1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31, 34, 37, 40, 43, 46, 49, 52, 55, 58, 61, 64, 67, 70, 73, 75, or 77, or a fragment thereof having acyl-ACP thioesterase activity.
Dependencies are inferred from the claim text.