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US 2014/0275285 A1Published application
Metadichol® liquid and gel nanoparticle formulations
AssigneeNanoRx, Inc.
InventorPalayakotai R. Raghavan
Life of this patent
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Abstract
The present invention provides methods of regulating physiological and metabolic parameters and of treating diseases by administering metadichol to a subject in need of such regulation and/or treatment. Metadichol can be administered as a liquid or gel formulation.
Claims12
An aqueous gel composition having substantial water-barrier properties, said gel comprising:
- (a) a water-soluble polymer;
- (b) Metadichol nanoparticles in a therapeutically effective concentration;
- and
- (c) water,
- said gel being free of a film-forming polymer, occlusive fats or oils.
2 more elements
A method of treating a disease by improving a physiologic or metabolic parameter in a subject, said method comprising:
- administering to said subject a therapeutically effective amount of a pharmaceutical formulation comprising metadichol nanoparticles, said parameter being a member selected from increasing serum APO A1 protein levels in said subject, reducing lipoprotein (a) (Lp(a)) in said subject, increasing hemoglobin level in said subject, increasing platelet count in said subject, reducing the level of uric acid in said subject, regulating e GFR level in said subject, regulating a member selected from absolute neutrophils, absolute monocytes and white blood cell level in said subject;
- reducing elevated AST:ALT ratios in said subject, reducing ferritin level in said subject, reducing bilirubin level in said subject, regulating thyroid hormone (TSH) level in said subject, and lowering the level of a member selected from PTH, calcium, creatinine, alkaline phosphatase Bun levels and serum phosphorus levels in the subject, thereby regulating said parameter in said subject.
Dependencies are inferred from the claim text.