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US 2014/0275258 A1Published application
Chelation Suppository for Improved Drug Delivery
AssigneeApplied Bioresearch, Inc.
InventorsRobert A. Settineri, Ernest H. Pfadenhauer
Life of this patent
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Abstract
Described herein is a method of delivering drugs to the blood stream directly by absorption through cell membranes in the wall of the rectum from a rectal suppository comprising a glyceride based excipient More specifically, CaNa2 EDTA is delivered rectally from a suppository containing water soluble, glyceride based excipient/carrier.
Claims12
A suppository for use in chelating heavy metals in a living being comprising:
- i. calcium disodium ethylenediaminetetraacetate (CaNa2 EDTA),
- ii. one or more hydrophobic excipients, and
- iii. a carrier comprising one or more of glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids, cocoa butter, and fatty acids.
A suppository for use in chelating heavy metals in a living being comprising:
- i. an EDTA containing compound, said EDTA compound being substantially micron or nanosized particles,
- ii. one or more hydrophobic excipients, and
- iii. a carrier comprising one or more of glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids, cocoa butter, and fatty acids.
A system for use in chelating heavy metals in a living being comprising:
- i. calcium disodium ethylenediaminetetraacetate (CaNa2 EDTA),
- ii. one or more hydrophobic excipients, and
- iii. a carrier comprising one or more of glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids, cocoa butter, and fatty acids.
Dependencies are inferred from the claim text.