Beraprost isomer as an agent for the treatment of viral infection
AssigneeGemmus Pharma Inc.
InventorsDARYL H. FAULDS, WILLIAM J. GUILFORD
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Abstract
In various embodiments the use of single isomer of beraprost as a therapeutic for the treatment of viral disease and other pathologies associated with the induction of a cytokine storm, such as influenza A viruses and the SARS-causing coronvirus and mutations thereof is provided.
Claims24
A method of treating a viral disease associated with the induction of immune response comprised of large amounts of pro-inflammatory cytokines such as IFN-γ, IL-10, IL-6, and CCL2, a ‘cytokine storm’, in a subject in need of such treatment, said method comprising administering, or causing to be administered, to the subject amount of a therapeutic agent effective to partially or fully suppress said cytokine storm.
A method of treating a viral disease that induces a cytokine storm in an individual, said method comprising administering to said individual a therapeutically effective amount of a prostacyclin analog.
A therapeutic composition comprising a therapeutic agent wherein said therapeutic agent comprises predominantly no more than two isomers of beraprost.
Dependencies are inferred from the claim text.