Cyclohexyl isoquinolinone compounds

A compound of formula (I):

• wherein
• R1 is halogen or cyano;
• q is 0, 1 or 2;
• R2 is:
• H,
• R8(R9)N—,
• R10—C(O)—, or
• where * marks the point of attachment to the rest of the molecule
• R5 is halo or cyano;
• R6 is
• (C1-C4)alkyl, wherein optionally one, several, or all of the hydrogen atoms are replaced with deuterium, and wherein said (C1-C4)alkyl is optionally substituted with 1, 2, 3 or 4 halo substituents, or
• (C1-C4)alkoxy(C1-C4)alkyl-;
• R7 is (C1-C7)alkyl, wherein optionally one, several, or all of the hydrogen atoms are replaced with deuterium;
• R8 is
• H,
• (C1-C4)alkyl, wherein said (C1-C4)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH,
• (C1-C4)alkyl-C(O)—, wherein said (C1-C4)alkyl-C(O)— is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH,
• R13(R14)N—C(O)—(CH2)n—, or
• HC(O)—;
• R9 is H, heterocyclyl2, or (C1-C7)alkyl, said (C1-C7)alkyl being optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH;
• or R8 and R9 together with the nitrogen atom to which they are attached form heterocyclyl1, said heterocyclyl1 being optionally substituted by 1 or 2 substituents independently selected from (C1-C4)alkyl and ═O;
• heterocyclyl1 is a 4, 5 or 6 membered saturated or partially unsaturated monocyclic ring, comprising ring carbon atoms and optionally 1 ring heteroatom independently selected from N, O and S in addition to the ring N atom to which R8 and R9 are attached;
• R10 is
• H,
• (C1-C6)alkyl, wherein said (C1-C6)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH,
• heterocyclyl2,
• phenyl, said phenyl being optionally substituted with 1 or 2 substituents independently selected from halo, cyano, OH and (C1-C4)alkyl, said (C1-C4)alkyl being optionally substituted with 1, 2 or 3 halo substituents, or
• heteroaryl2, said heteroaryl2 being optionally substituted with 1 or 2 substituents independently selected from halo and (C1-C4)alkyl, wherein said (C1-C4)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH;
• R11 is
• H,
• (C1-C7)alkyl, wherein said (C1-C7)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH,
• heterocyclyl2,
• phenyl, said phenyl being optionally substituted with 1 or 2 substituents independently selected from halo, cyano, OH and (C1-C4)alkyl, said (C1-C4)alkyl being optionally substituted with 1, 2 or 3 halo substituents,
• heteroaryl1, said heteroaryl1 being optionally substituted with 1 or 2 substituents independently selected from halo and (C1-C4)alkyl, wherein said (C1-C4)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH, or
• R13(R14)N—C(O)—(CH2)m—;
• m is 1 or 2;
• heterocyclyl2 is a 4, 5 or 6 membered saturated or partially saturated monocyclic group comprising ring carbon atoms and 1 or 2 ring heteroatoms independently selected from N, 0 and S;
• heteroaryl1 is a 5 or 6 membered fully unsaturated monocyclic group comprising ring carbon atoms and 1, 2, 3 or 4 ring heteroatoms independently selected from N, O and S, wherein the total number of ring S atoms does not exceed 1, and the total number of ring O atoms does not exceed 1;
• heteroaryl2 is a 5 membered fully unsaturated monocyclic group comprising ring carbon atoms and 1, 2, 3 or 4 ring heteroatoms independently selected from N, O and S, wherein the total number of ring S atoms does not exceed 1, and the total number of ring O atoms does not exceed 1;
• R12 is H, (C1-C4)alkyl, wherein said (C1-C4)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH;
• R13 is H or (C1-C4)alkyl, wherein said (C1-C4)alkyl is optionally substituted with 1, 2 or 3 substituents independently selected from halo, cyano and OH;
• R14 is H or (C1-C4)alkyl, wherein said (C1-C4)alkyl is optionally substituted with from one to three substituents independently selected from halo, cyano and OH;
• and
• n is 0, 1, 2 or 3.