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US 2014/0275136 A1Published application
Method of Treating a Proliferative Disease
AssigneeNovartis AG
InventorsDarrin Stuart, Meghna Das Thakur
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Abstract
The present invention relates to a method of treating a patient with a serine/threonine kinase inhibitor wherein resistance to the treatment with a serine/threonine kinase inhibitor is suppressed by administering the serine/threonine kinase inhibitor on an intermittent dosing schedule.
Claims5
A method of treating a proliferative disease characterized by a mutation in BRAF kinase, which comprises suppressing resistance to treatment with a BRAF inhibitor of the Formula II
- by administering the BRAF inhibitor of Formula II on an intermittent dosing schedule.
Use of a BRAF inhibitor of Formula II
- for the preparation of a medicament for the treatment of a proliferative disease whereby the BRAF inhibitor is administered on an intemittent dosing schedule.
Dependencies are inferred from the claim text.