Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
AssigneeLumena Pharmaceuticals, Inc.
InventorsBronislava GEDULIN, Michael GREY, Niall O'DONNELL, Bradley T. KELLER
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Abstract
Provided herein are methods of treating or ameliorating primary sclerosing cholangitis and inflammatory bowel disease by administering to an individual in need thereof a therapeutically effective amount of an Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTI) or a pharmaceutically acceptable salt thereof. Also provided are methods for treating or ameliorating primary sclerosing cholangitis comprising administering to an individual in need thereof a therapeutically effective amount of ASBTI or a pharmaceutically acceptable salt thereof.
Claims26
A method for treating or ameliorating primary sclerosing cholangitis and inflammatory bowel disease (PSC-IBD) in an individual comprising non-systemically administering to the individual a therapeutically effective amount of an Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTI) or a pharmaceutically acceptable salt or solvate thereof.
26-54. (canceled)
Dependencies are inferred from the claim text.