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US 2014/0274883 A1Published application
Novel antiviral compounds from marine extracts
AssigneesThe UAB Research Foundation, University of South Florida
InventorsAlberto VAN OLPHEN, Bill J. BAKER, Dennis E. KYLE, Cynthia BUCHER, Alan MASCHEK, James B. MCCLINTOCK, JR., Charles D. AMSLER
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Abstract
The subject invention pertains to novel biologically active extracts from marine algae and to biologically active fractions and components of these extracts. These extracts have been shown to possess antiviral properties. Pharmaceutical compositions comprising these extracts, or comprising biologically active fractions or components of these extracts, could be used in the treatment of viral diseases including influenza.
Claims20
An anti-viral protein comprising:
- 1) SEQ ID NO:1 (TLEVEASDTIENVK), or an amino acid sequence that has an amino acid substitution of, deletion from, and/or insertion into SEQ ID NO:1;
- 2) SEQ ID NO:2 (QDKEGIPPDQQRL), or an amino acid sequence that has an amino acid substitution of, deletion from, and/or insertion into SEQ ID NO:2;
- 3) SEQ ID NO:3 (QLEDGRTLSDYNIQKESTLHLVLRLRGG), or an amino acid sequence that has amino acid substitution of, deletion from, and/or insertion into SEQ ID NO:3, wherein a total of no more than two amino acids are substituted, deleted, and/or inserted;
- and
- 4) SEQ ID NO:4 (NGEFIEITEK).
2 more elements
Dependencies are inferred from the claim text.