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US 2014/0274796 A1Published application
Methods, Systems, and Compositions for In Vitro Concentric Cell Culture Analog Systems
AssigneeUniversity of Central Florida Research Foundation, Inc.
InventorJames J. Hickman
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Abstract
The present invention comprises methods, systems and compositions comprising concentric chamber cell culture analog devices, comprising biologically functional cells, which function similarly to in vivo conditions.
Claims20
An array of components, comprising:
- one or more culture analog system devices comprising one or more chambers and one or more sensing elements, wherein a chamber simulates at least one interorgan interaction, physiological condition, physical condition, chemical condition, or electrical condition of one or more whole organs, tissues, or organisms.
A method for determining the effect of an input variable on a culture system of cells, comprising:
- contacting at least one cell of a component or an array of components with an input variable,
- wherein the component or the array of components comprise one or more culture analog system devices comprising one or more chambers and one or more sensing elements, wherein a chamber simulates at least one interorgan interaction, physiological condition, physical condition, chemical condition, or electrical condition of one or more whole organs, tissues, or organisms;
- and
- monitoring at least one output parameter.
1 more element
Dependencies are inferred from the claim text.