NT-proANP AND NT-proBNP FOR THE DIAGNOSIS OF STROKE

A method for diagnosing an acute cerebral ischemic event in a subject who is suspected to suffer from an acute cerebral ischemic event, comprising:

• determining the amount of NT-proANP in a sample from said subject;
• determining the amount of NT-proBNP in a sample from said subject;
• and
• calculating a ratio of the amounts of NT-proANP and NT-proBNP.

A composition comprising:

• i) a NT-proANP and a NT-proBNP polypeptide;
• ii) a detection agent which specifically binds to the NT-proANP polypeptide and a detection agent which specifically binds to the NT-proBNP polypeptide;
• and
• iii) a blood, serum or plasma sample from a subject who is suspected to have exhibited an acute cerebral ischemic event.

A method of diagnosing an acute cerebral ischemic event, said method comprising:

• i) combining a sample from a subject who is suspected to have exhibited an acute cerebral ischemic event with a first detection agent which specifically binds to an NT-proANP polypeptide and a second detection agent which specifically binds to a NT-proBNP polypeptide;
• and
• 2) determining a ratio of binding of the first binding agent to the second binding agent;
• and
• 3) diagnosing whether the subject had an acute cerebral ischemic event.