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US 2014/0274792 A1Published application
Peptide and protein biomarkers for type 1 diabetes mellitus
AssigneeBattelle Memorial Institute
InventorsQibin Zhang, Thomas O. Metz
Life of this patent
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Abstract
A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.
Claims18
An array, comprising:
- a solid support;
- and
- antibodies specific for any combination of at least two, at least three, at least four, or at least five, type I diabetes mellitus (T1DM)-related protein sequences listed in Tables 6a or 6b, attached to the solid support,
A kit for diagnosing type I diabetes mellitus using mass spectrometry, comprising:
- one or more stable isotope labeled type I diabetes mellitus (T1DM)-related peptides listed in Tables 6a or 6b.
Dependencies are inferred from the claim text.