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US 2014/0274764 A1Published application
Method and system to predict response to treatments for mental disorders
AssigneePathway Genomics
InventorsGuangdan Zhu, Michael McCarthy, John Kelsoe, Cindy Wang, Tanya Moreno, Andrew Hellman, Alok Tomar, Svetlana Ivanova Gramatikova, Aditi Chawla, Russell Kuo-fu Chan, Andria Del Tredici, Adrian Vilalta, K. David Becker
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Abstract
The present inventions relates to methods and assays to predict the response of an individual to a psychiatric treatment and to a method to improve medical treatment of a disorder, which is responsive to treatment with a psychiatric treatment.
Claims21
A method for predicting an individual's likely response to a medication for a mental disorder, comprising genotyping genetic variations in an individual to determine:
- 1) a categorical grade to an individual's likely ability to metabolize a particular psychiatric medication, a categorical grade for a psychiatric medication's potential efficacy with respect to the individual, and a categorical grade to the propensity for the individual to have a negative adverse reaction to the particular psychiatric medication,
- 2) aggregating the categorical grades, and thereafter identifying the least positive grade as the recommended prediction for the individual.
21-30. (canceled)
Dependencies are inferred from the claim text.