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US 2014/0273274 A1Published application
Methods for the selective detection of alkyne-presenting molecules and related compositions and systems
AssigneeLawrence Livermore National Security, LLC
InventorsCarlos A. VALDEZ, Alexander K. VU
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Abstract
Provided herein are methods for selectively detecting an alkyne-presenting molecule in a sample and related detection reagents, compositions, methods and systems.
Claims14
A method for selectively detecting an alkyne-presenting molecule in an unprepared sample, the method comprising:
- contacting a detection reagent with the unprepared sample for a time and under a condition to allow binding of the detection reagent to the one or more alkyne-presenting molecules possibly present in the matrix to the detection reagent;
- wherein the detection reagent comprises an organic label moiety presenting an azide group and wherein binding of the azide group to the alkyne-presenting molecules results in emission of a signal from the organic label moiety.
A detection reagent comprising:
- one or more label organic moieties, the label organic moieties each presenting an azide group;
- wherein the label organic moieties are adapted to produce a signal when the detection reagent is bound to one or more alkyne-presenting molecules.
Dependencies are inferred from the claim text.