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US 2014/0273269 A1Published application
Rapid test for urine albumin and urine creatinine
AssigneeEpinex Diagnostics, Inc.
InventorsWing T. Liu, Thien-Toan Tran, John Scott, Thomas Lee, Srishti Prasad, Azra Zaidi
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Abstract
Disclosed herein is an immunochromatographic system for measuring albumin and creatinine in a urine sample and a reader that detects signals from the test cassette, calculates, and displays the results for albumin concentration, creatinine concentration, and albumin-creatinine ratio.
Claims20
A device for determining an albumin-creatinine-ratio in a human sample comprising:
- a test cassette comprising a test strip, wherein the test strip comprises;
- a single sample application pad containing a sample well disposed on the solid support;
- a conjugate pad having disposed therein a creatinine-specific conjugate and an albumin-specific conjugate;
- a lateral flow membrane;
- a creatinine-specific test region in which creatinine present in a sample and bound to the creatinine-specific conjugate is retained by a creatinine-specific immobilization agent associated with the membrane;
- a creatinine-specific control region in which the creatinine-specific conjugate which is not retained by the creatinine-specific test region is retained by a creatinine conjugate-specific immobilization agent associated with the membrane;
- an albumin-specific test region in which albumin present in the sample and bound to the albumin-specific conjugate is retained by an albumin-specific immobilization agent associated with the membrane;
- an albumin-specific control region in which the albumin-specific conjugate which is not retained by the albumin-specific test region is retained by an albumin conjugate-specific immobilization agent associated with the membrane;
- a reservoir;
- a measurement device to determine the concentration of albumin in the sample, the concentration of creatinine in the sample, and the albumin-creatinine-ratio.
7 more elements
Dependencies are inferred from the claim text.