Application of Ca Isotope Analysis to the Early Detection of Metastatic Cancer
AssigneeArizona Board of Regents on behalf of Arizona State University
InventorsAriel Anbar, Joseph Skulan, Gwyneth Gordon, Rafael Fonseca
Life of this patent
Estimating the term…
Abstract
Methods using the application of the Ca isotope method for diagnosing and monitoring the progression of cancers that cause bone loss. The methods also can be used for evaluating cancer treatments, such as aromatase inhibitors and other chemotherapeutic agents, for effects on bone density so that treatment can be modified.
Claims12
A method for the detection of cancer-related osteolytic and osteoblastic bone lesions, comprising:
- analyzing a bodily fluid of a patient through Ca isotope analysis;
- and
- detecting whether said fluid indicates a rate of change in bone mineral balance indicative of osteolytic and osteoblastic bone lesions.
A method for the detection of the metastasis of breast or prostate cancer to bone, comprising the steps of:
- analyzing a bodily fluid of a patient having breast or prostate cancer through Ca isotope analysis;
- and
- detecting whether said fluid indicates any decrease or increase in bone mineral balance based on said Ca isotope.
A method for monitoring changes in bone mineral balance in cancer patients, comprising:
- analyzing through Ca isotope analysis a bodily fluid of a patient being treated with one or more anti-cancer drugs or therapies;
- and
- detecting whether said fluid indicates a change in bone mineral balance.
Dependencies are inferred from the claim text.