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US 2014/0273179 A1Published application
Device for high throughput sperm sorting
AssigneeInguran, LLC
InventorsJohnathan Charles Sharpe, Nemanya Sedoglavich, Erin Koksal, Kris Buchanan, Blair Morad
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Abstract
This disclosure relates to a device in the form of a microfluidic chip. In particular, various features are incorporated into the microfluidic chip for aligning and orienting sperm in flow channels, as well as for separating selected subpopulations of sperm.
Claims32
A microfluidic chip for sorting sperm comprising:
- a substrate;
- a plurality of flow channels formed in the substrate, each flow channel comprising;
- an inlet;
- a fluid focusing region having an associated fluid focusing feature for aligning sperm cells within the flow channel;
- a sperm orienting region having an associated sperm orienting feature for orienting sperm cells within the flow channel;
- an inspection region at least partially downstream of the fluid focusing region and the sperm orienting region;
- at least a first outlet and a second outlet;
- and
- a diverting mechanism in communication with each flow channel.
6 more elements
Dependencies are inferred from the claim text.