Integrated Membrane for Preservation of Biomolecules
AssigneeChromoLogic LLC
InventorsNaresh Menon, Peter Bui, Cheryl Tan
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AssigneeChromoLogic LLC
InventorsNaresh Menon, Peter Bui, Cheryl Tan
Estimating the term…
An apparatus and method for moiety specific sample extraction from a complex sample matrix in a flow through process is provided. The present invention relates to an integrated membrane for separation and preservation of biomolecules. Classes of biomolecules, for example, those in blood, can be separated and preserved. For blood separation, the apparatus includes a housing having a matrix portion, and a fluid collection portion disposed within an inner cavity thereof. The housing also includes an aperture permitting access to the inner cavity. The apparatus also includes a matrix disposed within the matrix portion. The matrix includes a first layer for collecting substantially all cells from the fluid, a second layer for protein adsorption, and a third layer for nucleic acid adsorption. Fluid enters the housing through the aperture, passes through the matrix, and into the fluid collection portion. The method includes passing fluid through a matrix; collecting substantially all cells from the fluid in a layer of the matrix; adsorbing protein from the fluid in a layer of the matrix; and adsorbing nucleic acid from the fluid in a layer of the matrix.
An apparatus for preserving biomolecules, comprising:
A method for preserving biomolecules, comprising:
An apparatus for separating biomolecules, comprising:
An apparatus for preserving biomolecules, comprising:
Dependencies are inferred from the claim text.