Device And Method For Extracting A Targeted Fraction From A Sample
AssigneeWisconsin Alumni Research Foundation
InventorsDavid J. Beebe, Scott M. Berry
Life of this patent
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Abstract
A device and a method for isolating a target from a sample are provided. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes a first plate having a first region for receiving at least a portion of the sample. A second plate is spaced from the first plate by a distance and has a first region for receiving a reagent. A force attracts the target bound solid phase substrate toward the first region of the second plate such that the target bound solid phase substrate in the portion of the sample are drawn through the air gap and into the reagent by the force.
Claims25
A device for isolating a target from a sample, the target being bound to solid phase substrate to form target bound solid phase substrate, comprising:
- a first plate having a first surface and including a first region for receiving at least a portion of the sample;
- a second plate spaced from the first plate by a distance and having a first region for receiving a reagent;
- the second plate including a first surface directed toward the first surface of the first plate;
- and
- a force for attracting the target bound solid phase substrate toward the first surface of the second plate;
- wherein:
- the portion of the biological sample received by first region of the first plate is spaced from the reagent by an air gap;
- and
- the target bound solid phase substrate in the portion of the sample are drawn through the air gap and into the reagent by the force.
A device for isolating a target from a sample, the target being bound to solid phase substrate to form target bound solid phase substrate, comprising:
- a first sample receiving region for receiving at least a portion of the sample;
- a first reagent region for receiving a reagent, the first reagent region and the first sample region separated by an air gap;
- and
- a force for drawing the target bound solid phase substrate from the at least a portion of the sample, through the air gap and into the reagent.
A method for isolating a target from a sample, the target being bound to solid phase substrate to form target bound solid phase substrate, comprising the steps of:
- providing the sample at a region of a first plate;
- providing a reagent at a region of a second plate;
- and
- drawing the target bound solid phase substrate from the sample, through an air gap and into the reagent with a force.
Dependencies are inferred from the claim text.