Cell chips
AssigneesSamsung Electro-Mechanics Co., Ltd., Solidus Biosciences, Inc.
InventorsMoo-Yeal Lee, Se Hoon Jeong, Bo Sung Ku
Life of this patent
Estimating the term…
Abstract
Disclosed is a cell chip and methods for the use thereof, wherein the cell chip includes a substrate made of an opaque material and having a plurality of insertion holes formed therein, a filler made of a transparent material and inserted into each of the insertion holes so as to protrude from the substrate, and a biomatrix which is formed on the filler and immobilizes a biomaterial. Also, another substrate having a plurality of wells which store a fluid is further provided thus forming a 3D cell chip.
Claims27
A cell chip comprising:
- a substrate made of an opaque material and having a plurality of insertion holes formed therein;
- a filler made of a transparent material and inserted into each of the insertion holes so as to protrude from the substrate;
- and
- a biomatrix which is formed on the filler and immobilizes a biomaterial.
A cell chip, comprising:
- a lower substrate having a plurality of wells which store a fluid;
- an upper substrate, which is positioned above the lower substrate, is made of an opaque material and has a plurality of insertion holes formed therein;
- a filler made of a transparent material and inserted into each of the insertion holes so as to protrude from a lower surface of the upper substrate;
- and
- a biomatrix, which is formed on the filler, immobilizes a biomaterial, and is inserted into each of the wells.
A method of detecting the effect of a test agent on cells comprising bringing into contact a fluid comprising said test agent and an upper substrate, which is positioned above the lower substrate, is made of an opaque material and has a plurality of insertion holes formed therein;
- wherein a filler made of a transparent material is inserted into each of the insertion holes so as to protrude from a lower surface of the upper substrate;
- and wherein a biomatrix, which is formed on the filler, immobilizes said cells, and is inserted into each of the wells, wherein said fluid and said test agent are brought into contact for a time sufficient for reaction between the cells and the test agent, said method further comprising detecting the effect of the test agent on the said cells.
Dependencies are inferred from the claim text.