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US 2014/0272989 A1Published application
Reagent wells containing lyophilized reagents
AssigneeGen-Probe Incorporated
InventorByron J. KNIGHT
Life of this patent
Estimating the term…
Abstract
System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
Claims18
A reagent well comprising:
- a side wall, a bottom wall, and an open upper end;
- a lyophilized reagent disposed within the well;
- and
- a retention feature disposed within the well above the lyophilized reagent, wherein the retention feature provides an opening therethrough, and wherein the opening is smaller than the size of the lyophilized reagent, thereby retaining the lyophilized reagent within the well.
1 more element
A reagent well comprising:
- a side wall, a bottom wall, and an open upper end;
- a capillary insert in contact with or part of the side wall and including a capillary channel extending therethrough;
- and
- a lyophilized reagent disposed within the capillary channel.
1 more element
A method of providing a stabilized reagent in a cartridge for use in an automated process, the method comprising:
- (a) introducing a liquid reagent to a capillary channel of a capillary insert disposed within or an integral part of a reagent well, wherein at least a portion of the liquid reagent is retained within the capillary channel;
- and
- (b) subjecting the reagent well and the liquid reagent retained with the capillary channel to conditions suitable for lyophilizing the liquid reagent, thereby forming a lyophilized reagent within the capillary channel that can be reconstituted by introducing a reconstitution solution to the capillary channel to form a reconstituted reagent.
Dependencies are inferred from the claim text.